Rob Reiner's final television appearance before his death was in a sketch portraying George Washington, which aired as part of the episode "Life, Larry and the Pursuit of Unhappiness." The segment, which has gained traction on social media since its Friday broadcast, features Reiner alongside Larry David in a satirical discussion that appears to target former President Donald Trump.

In the sketch, Reiner's George Washington declares his intention not to seek a third term, emphasizing the importance of this precedent for the fledgling democracy.

David, appearing as an audience member, interjects with concerns about a hypothetical future president who might disregard this tradition.

This development is significant as it marks Reiner's last on-screen performance, offering a final glimpse of his work in a politically charged comedic context.

David's character escalates the hypothetical scenario, questioning what would happen if a "narcissistic pr*ck" ignored constitutional limits or if the Supreme Court and Congress failed to act as checks on power.

He further speculates about a president who might use the office for personal enrichment, deploy troops against citizens, or attack the free press, even suggesting a connection to a pedophile, alluding to various controversies.

Jimmy Kimmel makes a surprise cameo in the sketch as another early American, initially expressing disbelief at David's dire predictions.

Kimmel's character then questions if a president would challenge critics "as if he were a big baby," to which David responds by describing such a figure as an "insecure, lying assh*le who would even cheat at golf!" The sketch culminates in a brawl among the audience, with Reiner's Washington attempting to restore order before concluding with the line, "We're f*cked."

Reiner was found deceased alongside his wife, Michelle Reiner, in December 2025.

Their son, Nick, has been arrested in connection with their deaths and is currently awaiting trial.